Comparative Analysis of Substituted Feed Antibiotics for Feed AcidifierHite  Publish time :2017-08-10
Antibiotics as feed additives have been used for more than half a century of history, with people concerned about food safety. Antibiotics are gradually replacing the call is getting higher and higher, so feed acidifier and other feed additives application research is also increasing. On the application of antibiotics and acidifier for a comparative analysis for feed producers and farmers to choose the reference, thereby enhancing the economic benefits of farming.
1, antibiotics have a positive effect
1.1 on the treatment of certain diseases of animals
For the control of the disease. Promote the healthy growth of animals is extremely important. This is the normal pharmacological effect of antibiotics.
1.2 on the prevention of certain diseases of animals
Prevent infectious diseases, to ensure the healthy growth of livestock and poultry. The application of salinomycin can prevent the occurrence of coccidiosis.
1.3 to promote growth
So that the growth rate of livestock and poultry to speed up, that is, the role of fattening, can make some animal breeding cycle shortened ahead of slaughter.
1.4 improve feed conversion rate
So that in the same feed conditions to achieve a different feeding effect, or use less feed to achieve the same feeding effect. Thus saving feed, improve efficiency.
1.5 to improve the production of animal products
So that egg-producing animals and more eggs, milk production of milk production, hair-producing animals and other hair.
1.6 improve the quality of animal products
Can improve the quality of meat and milk products, including raising the survival rate of cubs.
1.7 improve the animal breeding environment
Including the reduction of various pathogens in the environment, animal fecal excretion and changes in the nature of feces.
1.8 improve the performance of animal body state
That is to improve the resistance of animal body. Thereby enhancing the ability of animals to cope with adverse environmental conditions and reducing the loss of animals due to various stress reactions.
Hays (1978) and Zimmermann (1986) summarize the test of about 1200 feed antibiotics applied to pigs. The results show. The addition of sub-therapeutic doses of antibiotics to livestock and poultry feeds is positive for improving the performance of animals. But at the same time its long-term use as a feed additive is also controversial.
2, the negative effects of antibiotics
2.1 allergic reactions and allergic reactions
Allergic symptoms are varied. When some antimicrobial agents remain in the meat after entering the human body. Can make some sensitive people allergic reactions.
2.2 tricolor effect
Triadism that carcinogenic, teratogenic, mutagenic effect. When people eat long-term animal food containing animal residues, these residues will have harmful effects on the human body, or in the human body accumulation, and ultimately produce carcinogenic, teratogenic, mutagenic effect, in recent years, the incidence of cancer in the crowd continued Rise. This is related to environmental pollution and drug residues in animal foods.
2.3 on the effects of gastrointestinal flora
Normal body parasitic with a large number of flora, if the long-term and animal food in the low dose of antimicrobial residues in contact, it will inhibit or kill sensitive bacteria, resistant bacteria or conditional pathogens mass reproduction. The microbiological balance was destroyed. So that the body prone to infectious diseases.
2.4 bacterial resistance increased, to bring pressure on new drug development
Add antibiotics to the feed. Actually equal to sustained low-dose medication. Animal body long-term contact with drugs. Resulting in increasing drug-resistant bacteria. Drug resistance is also increasing. Antibacterial drugs remain in animal foods. The same people long-term contact with drugs, leading to the increase in drug-resistant bacteria in the human body. now. Whether it is in animals. Or in the human body. Bacterial resistance has reached a more serious degree. Due to drug abuse. The rate at which bacteria produce resistance is accelerating. Drug resistance has also been strengthened. Which makes the life of antimicrobial drugs gradually become shorter. It is not easy to develop a new drug.
2.5 Difficulty in clinical diagnosis and treatment of diseases
Long - term exposure to certain antibiotics. Can make the body humoral immunity and cellular immune function decline, resulting in a variety of lesions, or medication when the side effects. To the clinical diagnosis and treatment difficult. Clinical pathogens resistant to the increasing. So that the efficacy of antibiotics is getting lower and lower. In animal breeding. When an infectious disease occurs. If the use of several antimicrobial drugs are invalid. Not only increased the feeding costs. And to prolong the course of the disease. Affecting the performance of animals, so that farming profits decline, and even lose everything.
2.6 Drug residues and ecological environment
With the strengthening of environmental awareness in the world. People are increasingly concerned about the accumulation of antibiotics in the environment, transfer, transformation and the impact on various biological and human health.
The study found. Abuse of antibiotics has brought more and more trouble to mankind. Feeding long-term antibiotics can lead to many adverse consequences. Low doses of antibiotics into the environment for a long time, will cause increased resistance to susceptible strains. With the increase in animal food demand and food safety attention, people gradually recognized the disadvantages of feeding antibiotics. Antibiotic residues are increasingly becoming public health issues of common concern to society as a whole. Therefore, the search for alternatives to feed antibiotics has become a hot topic for experts around the world.
At present, feed acidifier has been widely used in developed countries, and become an important feed additive for alternative antibiotics.